Latest Lung Cancer: Small Cell News

Schizophrenia Associated with Increased Cancer Mortality (07/24/2009)
Patients with schizophrenia appear to have an increased risk of mortality from cancer, especially breast cancer in women and lung cancer in men, according to the results of a study published in Cancer.

Thalidomide Doesn’t Benefit Patients with Small Cell Lung Cancer (07/22/2009)
Treatment with a combination of thalidomide and chemotherapy did not improve survival among patients with small cell lung cancer, and resulted in a higher risk of blood clots than treatment with chemotherapy alone. The results of this study were published in the Journal of the National Cancer Institute.

False-positive Results Are Common with Cancer Screening (07/20/2009)
The risk of obtaining a false-positive result from screening for prostate, lung, colorectal, and ovarian cancer is high and becomes cumulatively higher with ongoing screening—after 14 screening tests, the cumulative risk of a false-positive is 60.4% for men and 48.8% for women, according to the results of a study published in the Annals of Family Medicine.

Lung Cancer Screening with Low-dose Computed Tomography Associated with High Rate of False Positives (06/10/2009)
Individuals who undergo lung cancer screening with low-dose computed tomography (LDCT) are at a high risk for receiving false-positive results, according to the results of a study presented at the 2009 annual meeting of the American Society of Clinical Oncology in Orlando, Florida.

Removal of Ovaries During Hysterectomy for Benign Condition Carries Health Risks (05/12/2009)
Among women who have a hysterectomy for reasons other than cancer, those who also have their ovaries removed have a slightly higher overall risk of death from cancer and heart disease than those who do not have their ovaries removed. These results were published in Obstetrics and Gynecology.

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Latest Lung Cancer: Small Cell by Stage
Extensive

Thalidomide Doesn’t Benefit Patients with Small Cell Lung Cancer (07/22/2009)
Treatment with a combination of thalidomide and chemotherapy did not improve survival among patients with small cell lung cancer, and resulted in a higher risk of blood clots than treatment with chemotherapy alone. The results of this study were published in the Journal of the National Cancer Institute.

Gemzar® and Paraplatin® Equivalent to Platinol® and VePesid® for SCLC (12/30/2008)
A combination of Gemzar® (gemcitabine) and Paraplatin® (carboplatin) is as effective as standard Platinol® (cisplatin) and VePesid® (etoposide) for palliative treatment of patients with poor-risk small cell lung cancer (SCLC).  The Gemzar/Paraplatin combination is also less toxic, according to the results of a study published in an early online publication of Thorax on September 11, 2008.

Non-Platinum Chemotherapy as Effective for SCLC (10/14/2008)
Chemotherapy regimens that do not contain platinum agents (Platinol and Paraplatin) appear to be just as effective as regimens that do contain platinum agents in the treatment of small cell lung cancer. These results were recently published in the Cochrane Database of Systematic Reviews.

VePesid®/Platinol® Remains Standard-of-care for Small Cell Lung Cancer (06/07/2008)
For patients diagnosed with extensive-stage small-cell lung cancer (SCLC), the standard-of-care remains the chemotherapy combination of VePesid® (etoposide) and Platinol® (cisplatin). A recent study indicates that Camptosar® (irinotecan) plus Platinol does not improve survival in SCLC compared with VePesid/Platinol. These findings were presented at the 2008 annual meeting of the American Society of Clinical Oncology.

Higher Chemotherapy Dose Intensity Does Not Improve Survival for Small Cell Lung Cancer (04/21/2008)
Increasing the dose intensity of chemotherapy does not appear to improve survival in small cell lung cancer. These results were recently published in the Journal of the National Cancer Institute.

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Limited Disease

Thalidomide Doesn’t Benefit Patients with Small Cell Lung Cancer (07/22/2009)
Treatment with a combination of thalidomide and chemotherapy did not improve survival among patients with small cell lung cancer, and resulted in a higher risk of blood clots than treatment with chemotherapy alone. The results of this study were published in the Journal of the National Cancer Institute.

Non-Platinum Chemotherapy as Effective for SCLC (10/14/2008)
Chemotherapy regimens that do not contain platinum agents (Platinol and Paraplatin) appear to be just as effective as regimens that do contain platinum agents in the treatment of small cell lung cancer. These results were recently published in the Cochrane Database of Systematic Reviews.

Higher Chemotherapy Dose Intensity Does Not Improve Survival for Small Cell Lung Cancer (04/21/2008)
Increasing the dose intensity of chemotherapy does not appear to improve survival in small cell lung cancer. These results were recently published in the Journal of the National Cancer Institute.

Advances in the Management of Small-Cell Lung Cancer (03/25/2008)
Highlights from the 12th World Conference on Lung Cancer 

PET Scans May Help Identify Early Lung Cancer (11/28/2007)
According to an article recently published in the Journal of the National Cancer Institute, positron emission tomography (PET) scans may improve the accuracy of imaging in lung cancer.

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Recurrent

Oral Hycamtin® Approved for Relapsed Small Cell Lung Cancer (10/15/2007)
The United States Food and Drug Administration has approved an oral capsule formulation of the chemotherapy agent Hycamtin® (topotecan) for the treatment of relapsed small cell lung cancer.

Further Results Show Improved Survival with Picoplatin for Small Cell Lung Cancer (09/04/2007)
According to results published in a press release by Poniard Pharmaceuticals, longer follow-up further indicates that the investigative chemotherapy agent picoplatin may improve survival compared to existing therapies in the treatment of patients diagnosed with small cell lung cancer who have previously received platinum-based therapies.

Addition of Gliadel® Wafer to Surgery and Radiation Effective for Brain Metastasis (06/22/2007)
According to an article in Clinical Cancer Research, the addition of Gliadel® Wafer (carmustine polymer wafer) to surgery plus external beam radiotherapy for the treatment of a single brain metastasis is a safe and effective regimen for patients.

Hycamtin® Improves Survival in Patients with Relapsed Small Cell Lung Cancer (12/06/2006)
According to the results of a study published in the Journal of Clinical Oncology, patients with relapsed small cell lung cancer survived longer if they were treated with the oral chemotherapy drug Hycamtin® (topotecan) than if they received no further chemotherapy.

Amrubicin Shows Promise in Relapsed or Refractory Small Cell Lung Cancer (11/30/2006)
According to a study published in the Journal of Clinical Oncology, treatment with the experimental chemotherapy drug amrubicin reduced or eliminated detectable cancer in roughly half of patients with previously-treated small cell lung cancer.

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Screening/Prevention

Schizophrenia Associated with Increased Cancer Mortality (07/24/2009)
Patients with schizophrenia appear to have an increased risk of mortality from cancer, especially breast cancer in women and lung cancer in men, according to the results of a study published in Cancer.

False-positive Results Are Common with Cancer Screening (07/20/2009)
The risk of obtaining a false-positive result from screening for prostate, lung, colorectal, and ovarian cancer is high and becomes cumulatively higher with ongoing screening—after 14 screening tests, the cumulative risk of a false-positive is 60.4% for men and 48.8% for women, according to the results of a study published in the Annals of Family Medicine.

Lung Cancer Screening with Low-dose Computed Tomography Associated with High Rate of False Positives (06/10/2009)
Individuals who undergo lung cancer screening with low-dose computed tomography (LDCT) are at a high risk for receiving false-positive results, according to the results of a study presented at the 2009 annual meeting of the American Society of Clinical Oncology in Orlando, Florida.

Removal of Ovaries During Hysterectomy for Benign Condition Carries Health Risks (05/12/2009)
Among women who have a hysterectomy for reasons other than cancer, those who also have their ovaries removed have a slightly higher overall risk of death from cancer and heart disease than those who do not have their ovaries removed. These results were published in Obstetrics and Gynecology.

Smoking Kills More Than 440,000 People Each Year in the United States (04/24/2009)
According to an analysis by the U.S. Centers for Disease Control and Prevention (CDC), cigarette smoking and exposure to tobacco smoke cause at least 443,000 premature deaths each year in the United States alone. These results, based on data from 2000-2004, were published in the Morbidity and Mortality Weekly Report.

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